ROLE OF INTERLEUKINS IN THE ETIOPATHOGENESIS OF PERIODONTAL DISEASES

Rupali Mahajan, Kanupriya Sharma, Swati Bhalla, Rohit Vashisht, Neha Kalia

Abstract


Periodontitis is an infectious disease that results in the destruction of the structures that support  the teeth, namely, alveolar bone and connective tissue attachment to teeth. It is initiated by pathogenic bacteria, which trigger an inflammatory response that is effective in preventing significant microbial colonization of the gingival tissues. In some individuals, the reaction to bacteria may lead to an excessive host response, resulting in periodontal tissue destruction.

 

Cytokines play an important role in the pathology associated with chronic inflammatory diseases. The cytokines which are molecularly and chemically well defined are called interleukin and different interleukins play a significant role in the pathogenesis of periodontitis. In this review article the specific  roles of different interleukins are hereby explained.


Keywords


Cytokines , Interleukins , Periodontal Disease , Inflammatory disease

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